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But COVID-19 vaccine protects most cancer patients from COVID or severe cases; people with blood cancer don’t get the same protection benefits, study in Indiana University Melvin and Bren Simon Cancer Center in Indianapolis.
Vaccinated blood cancer patients may be at “higher and more diverse risk” of developing breakthrough COVID infections, according to a study published in the Journal of Clinical Oncology.
“Patients with blood cancers or blood cancers, including leukemia, multiple myeloma, and lymphoma, are at higher risk for COVID breakthrough,” the researchers said in a statement sent to Fox. Higher risk for solid cancers” news on the study.
FILE – A nurse checks IV fluids while talking to a COVID-19 patient at Providence Holy Cross Medical Center in Los Angeles
(AP Photo/Jae C. Hong, File)
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The study’s lead investigator, Jing Su, Ph.D., assistant professor in the Department of Biostatistics at Indiana University School of Medicine, led a team of researchers from 10 research institutions across the country to analyze data from the National COVID Cohort Collaboration (N3C) at the National Institutes of Health. .
According to the statement, the researchers found that the risk of breakthrough infection decreased after all cancer patients received a second dose of the vaccine. The team also said in the report that “Moderna’s vaccine was more effective than Pfizer’s vaccine in protecting patients with hematological cancers, especially multiple myeloma.”
A worker in a protective suit holds a sign reading “Don’t Crowd” as he directs residents near the first round of mass COVID-19 testing lines in Jing’an District, western Shanghai, China, Friday, April 1, 2022. As western residents of Shanghai begin its four-day mass testing lockdown, some residents in eastern Shanghai who are about to end the lockdown say they will be confined to their homes for at least 10 days. As part of China’s zero-coronavirus policy, it is working to contain the coronavirus outbreak caused by the omicron, the latest in a lockdown of China’s largest city.
(AP Photo/Chen Si)
The team used one of the largest real-world sources of COVID data, and the largest in the United States, the statement said. Su, who is also senior associate director of real-world data at the Cancer Center’s Biostatistics and Data Management Core, said the study included more than 12.5 million patients and 4.5 million patients. The team has screened more than 64,000 cancer patients who have been vaccinated against COVID-19, the statement said.
“We systematically examined the main type of cancer and main type of treatment, as well as other risk factors such as age, comorbidities, gender, ethnicity, geographic location, etc., to qualitatively understand the contribution and specific rates of each risk factor for each cancer Subgroups as well as the contribution of treatment classes to cancer patients,” Su said in a press release. The researchers also explained that this analysis was possible because the team had a large COVID cohort and a control group.
People line up for a COVID-19 test in Los Angeles on January 4, 2022. Scientists are seeing signals that alarming micron waves of COVID-19 may peak in the UK and are on the verge of reaching the same level in the US, at which point cases could start to drop sharply.
(AP Photo/Jae C. Hong, File)
The findings may help guide clinical care and treatment of COVID-19 cancer patients, and beyond this pandemic, the findings may also aid in the development of cancer treatments, the study reports. Because immunotherapy treatments rely on the ability of a person’s immune system to fight disease, the results can help predict which patients will benefit from a particular type of cancer treatment, the researchers explained.
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“Indeed, the COVID-19 pandemic presents us with a unique opportunity to screen all cancer patients across the country for immunity,” Su said in the statement. “We can use it to model the different immune capacities of cancer patients. This can help us better understand whether cancer patients respond well to cancer vaccines, and whether they are at higher risk of contracting other viruses, such as the flu .. »
The team is now studying the effectiveness of weakened immunity and booster shots, especially as new COVID variants such as BA.2 emerge.
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“We are monitoring the situation to see what the new variant means for cancer patients and how best to protect them through vaccination. »