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Omicron infects young children more easily than other variants; loss of smell may be precursor to memory loss – zimo News

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Below is a summary of some recent studies on COVID-19. These include studies that deserve further research to confirm the findings and that have not yet been certified by peer review.

Children’s noses have poor defenses against Omicron

A variant of Omicron may be more effective at infecting children through the nose than previous versions of the coronavirus, a small study suggests.

Early in the pandemic, children’s noses were less resistant to the virus that causes COVID-19 than adults’ noses. Studies of the original SARS-CoV-2 and some of its variants have found that the virus encounters a stronger immune response in cells lining the nose of young adults than in adult nasal cells, and reproduces less efficiently in children. nose. But a recent test-tube experiment that mixed the virus with nasal cells from 23 healthy children and 15 healthy adults found that antiviral defenses in the children’s noses were “significantly less in Omicron’s case,” the researchers reported Monday in PLOS Biology. obvious”. They also reported that Omicron replicated more efficiently in children’s nasal cells compared to Delta virus and the original virus.

As OMICRON’s BA.5 sub-variant on the rise, vaccine experts urge at-risk groups to get immediate COVID-19 booster

“These data are consistent with the observed increase in the number of pediatric infections during Omicron waves,” the researchers wrote, calling for more research.

Two young children wearing face masks play in the snow in Bryant Park during the COVID-19 pandemic in Manhattan, New York City, U.S., January 14, 2022.
(Reuters/Carlo Allegri)

Smell problems may predict memory problems after COVID-19

The severity of olfactory dysfunction following coronavirus infection may be a better predictor of long-term cognitive impairment than the overall severity of COVID-19, according to an Argentine study.

The researchers surveyed a random sample of 766 people over the age of 60, and about 90 percent of them had the virus. Physical, cognitive and neuropsychiatric tests performed three to six months after infection showed some degree of memory impairment in two-thirds of the infected participants. The severity of anosmia (called anosmia) after accounting for an individual’s other risk factors, “but not a clinical condition, is,” the researchers reported Sunday at the 2022 Alzheimer’s Association International Conference, held online. Significant (predicted) cognitive impairment” in San Diego.

“The more we know about the cause, or at least predict who will experience the significant long-term cognitive impact of COVID-19 infection, the better we can track it and start developing ways to prevent it,” said Gabriela Gonzalez, the group’s head Research. Aleman, from the Catholic University of Argentina in Buenos Aires, said in a statement.

Vaccine mandate linked to better nursing home staffing

A study found that in U.S. states that have mandated COVID-19 vaccinations for nursing home workers, the rules have had the desired effect and have not led to mass layoffs or staffing shortages.

However, in states without such regulations, nursing homes experienced staffing shortages during the study period, researchers at the JAMA Health Forum reported Friday. Data collected from the National Healthcare Safety Network from mid-June to mid-November 2021 shows that in 12 states with COVID-19 vaccination mandates, worker vaccination coverage ranges from 78% to 7% to 95.2% not wait. Non-authorized states “had consistently lower rates of staff immunization coverage throughout the study window” and “reported higher rates of staff shortages throughout the study period,” the report said.

The BA.5 variant of OMICRON may cause a higher risk of reinfection and severe consequences compared to other variants

“These regulations are associated with higher vaccine coverage, which contrasts with previous efforts to increase COVID-19 vaccination among nursing home workers through education, outreach and incentives,” the officials said. They added that the data “suggests that fears of significant staffing shortages due to vaccination requirements may be unfounded”.

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